
Hello.
I am Dr. Kim Dong-young, Director of Cleor Clinic Hongdae Branch.
Have you ever felt that the fine lines around your eyes are increasing every time you look in the mirror,
or have you ever been concerned that the skin under your eyes looks thin no matter how much eye cream you apply?
"I apply eye cream diligently for eye care, but there is no significant difference.
I wonder if there is a way to fundamentally improve fine lines under the eyes and thinned skin."
Compared to other parts of the face, the eye area has very thin skin,
is vulnerable to dryness due to fewer sebaceous glands, and is an area where damage easily accumulates
due to frequent facial expressions.
Because of these unique characteristics of the eye area, it is often difficult to achieve fundamental improvement
with general skincare, and an approach that regenerates the skin tissue itself is suitable,
and this approach is Hongdae Rejuran i.
Today, I will explain why Rejuran i is specialized for the eye area,
how the PN ingredient induces tissue regeneration,
and how it differs from other eye treatments.
What is Hongdae Rejuran i

👉 Hongdae Rejuran i is a skin booster treatment that injects PN (polynucleotide) ingredients refined from salmon DNA, formulated specifically for the eye area, into the dermis to fundamentally regenerate thinned eye skin tissue.
Rejuran is a PN-based skin booster treatment developed by PharmaResearch.
While existing skin boosters focus on moisture or collagen stimulation,
Rejuran is different because it regenerates the skin tissue itself.
Rejuran i is a treatment specifically formulated for the eye area among them.
Compared to regular Rejuran, it has a composition suitable for the thin and sensitive skin around the eyes,
allowing for precise care that considers the unique characteristics of the eye area.
At the Hongdae branch, we offer 1-session and 3-session options for Rejuran i, which include cryotherapy and a sheet mask,
so you can proceed according to your regular care plan.
Principles of the PN (polynucleotide) ingredient
👉 The core ingredient of Hongdae Rejuran i, PN, is a substance refined from salmon DNA that works on the principle of naturally inducing cell regeneration and
tissue recovery.
What is PN
PN (Polynucleotide) is a biological polymer substance in which nucleotides are linked.
It has the same composition as the basic units of genetic materials like DNA and RNA in our body,
so it is a highly biocompatible ingredient.
The PN used in Rejuran is a highly refined substance extracted from salmon testes,
and the risk of allergic reactions is managed to be very low during the refining process.
Mechanism of action
When PN is injected into the dermis, it binds to cell surface receptors,
activating signals for cell regeneration, tissue recovery, and anti-inflammatory effects.
In this process, collagen and elastin synthesis are promoted,
and the skin's own regenerative ability is activated.
Difference from other skin boosters
If general HA skin boosters are specialized for hydration,
Rejuran's PN is fundamentally different as it regenerates the skin tissue itself.
It is not a problem caused by a lack of moisture,
but from the perspective of improving the state where the skin tissue itself has thinned and been damaged,
the strengths of PN are distinct.
Unique characteristics of eye skin - Why is a specialized eye treatment necessary?
👉 The eye area has the thinnest skin on the face, has few sebaceous glands, is vulnerable to dryness, and is an area where damage easily accumulates due to frequent facial expressions, making fundamental improvement difficult with general skincare.

The thinnest skin on the face
The skin around the eyes is characterized by being much thinner than other parts of the face.
As it is thin, it is vulnerable to damage, fine lines easily settle in,
and it is an area that requires the restoration of skin thickness itself.
Lack of sebaceous glands and dryness
The eye area has very few sebaceous glands, making it difficult to maintain moisture on its own.
If dryness persists, it leads to deepening fine lines and a decline in skin condition.
Frequent facial expressions
We blink our eyes thousands of times a day and make various facial expressions.
These frequent movements accumulate micro-damage around the eyes
and become the root cause of fine lines.
Specialized composition of Rejuran i
Rejuran i is an eye-specific product formulated considering these unique characteristics of the eye area.
Unlike regular Rejuran, it is designed with a concentration and composition suitable for the eye area,
so it can be safely applied to thin and sensitive eyes.
Management approach of Hongdae Rejuran i
👉 Hongdae Rejuran i is a management method that proceeds with Rejuran i 1cc manual injection, cryotherapy, and a sheet mask,
and each step is combined to approach eye regeneration and soothing together.
Rejuran i 1cc manual injection
Professional medical staff precisely inject 1cc of Rejuran i into the eye area.
It is performed using a detailed manual injection method considering the sensitive characteristics of the eye area,
and it is a method of distributing it evenly in small amounts at multiple points.
Cryo soothing
After the treatment, the eye area is soothed with cryo (cooling) care.
It quickly relieves redness and micro-swelling immediately after the injection,
and it is a step that helps restore skin condition.
Sheet mask finish
It is finished with a moisturizing sheet mask to soothe the stimulated eye skin,
and it is a finishing care that helps with ingredient absorption and condition stabilization.
Hongdae Rejuran i lineup
👉 At the Hongdae branch, we operate Rejuran i 1cc in 1-session and 3-session options,
and proceed with a program that includes cryo and sheet mask care.
Generally, when performed regularly 3 or more times at 2-4 week intervals,
the results of eye regeneration settle stably.
Rather than immediate results from a single treatment, as sessions accumulate,

the eye skin gradually recovers,
so consistent regular care is important for satisfaction with the results.
Your eye condition, management goals, and session plan
will be examined together during the preliminary consultation.
Who is Rejuran i suitable for?
Those who have started to develop fine lines around the eyes
Those who feel that fundamental improvement is difficult with eye cream
Those whose skin under the eyes is thin, making blood vessels visible
Those who are concerned about dark circles and eye area condition
Those who want low-irritation care for sensitive eyes
Those who want to maintain eye area condition with regular care
Side effects of Hongdae Rejuran i and things to know in advance
👉 Hongdae Rejuran i is a management treatment using the human-friendly PN ingredient, but
since it is a treatment for the sensitive eye area, the practitioner's precise manual skill is decisive for the stability of the results.
Immediately after the treatment, light redness, micro-swelling, and thin bruising may settle in the treated area for a few days.
Generally, it clears up naturally within a few days,
but since the eye area is an area where blood vessels are concentrated, there is a possibility that micro-bruising may remain,
so it is necessary to adjust the timing during the preliminary consultation before important schedules.
Rejuran i is performed by manual injection,
so the practitioner's precise judgment and manual skill are especially important.
Because it must be distributed evenly in the exact layer of the eye area for the results to settle stably,
the treatment direction is decided after checking your eye condition
in the preliminary consultation according to the guidance of experienced medical staff.
Although PN is a highly biocompatible ingredient refined from salmon DNA,
rarely, there may be individual allergic reactions,
so checking your allergy history before the treatment is important.
Since the results after the treatment are a method that gradually settles as sessions accumulate,
it is a flow where stable improvement is confirmed through regular sessions rather than dramatic changes immediately after the treatment.
If you fall under the following, the treatment may be restricted or
prior confirmation may be required, so please inform us during the consultation.
If you are pregnant or breastfeeding
If there is an active infection, wound, or herpes in the treatment area
If you have a history of salmon or seafood allergies
If you are regularly taking anticoagulants or antiplatelet agents, or have a bleeding tendency
If you have been diagnosed with an autoimmune disease or keloid constitution
If you have a history of filler or thread treatments in the eye area recently
⚠️ Precautions before and after Rejuran i treatment
👉 Rejuran i is a treatment where result stability and recovery speed vary depending on pre-treatment condition management and post-treatment UV and moisturizing care.
❓ Frequently Asked Questions (FAQ)
Q. When can I see the results of Hongdae Rejuran i?
Improvement in eye condition is gradually confirmed from 2-3 weeks after the treatment,

and when performed regularly 3 or more times, improvements in fine lines, skin thickness, and dark circles accumulate.
Since PN ingredients induce tissue regeneration,
the results become clearer as sessions accumulate.
Q. How is regular Rejuran different from Rejuran i?
Both treatments are based on PN ingredients, but the composition is different.
Rejuran i is designed with a composition suitable for thin and sensitive eyes,
and it is a precisely adjusted product so that it can be safely applied to the eye area.
It is a treatment more specialized for the eye area than regular Rejuran.
Q. I have a salmon allergy, can I receive it?
Although it is an ingredient refined from salmon DNA, in the highly refined process,
the allergy-causing protein is removed.
However, if you have a severe seafood allergy,
checking your allergy history during the preliminary consultation is necessary,
and other treatment options are reviewed if necessary.
Q. Can it be combined with other eye treatments?
Yes, it is possible.
Rejuran i is specialized for tissue regeneration,
so it does not overlap in principle with other eye treatments such as Eye Ulthera (lifting) or Juvellook Eye (volume filling),
and there is a synergistic effect when combined.
The treatment order and interval are decided during the preliminary consultation.
Q. How much pain is there?
It is performed after applying anesthetic cream before the treatment, so there is no strong pain.
It is injected by manual injection at multiple points in small amounts with a thin needle,
and it is a flow where irritation is soothed with cryo and sheet mask care after the treatment.
Q. How long do swelling and bruising last after the treatment?
Generally, it clears up naturally within a few days.
Since the eye area is an area where blood vessels are concentrated, micro-bruising may remain,
so it is suitable to avoid the treatment 1 week before important schedules.
Q. When can I wear makeup after the treatment?
Mild eye makeup is possible from the evening of the day of the treatment.
It is good for recovery stability to refrain from cosmetics with strong irritation to the eye area or
heavy eye makeup for a few days.
The eye area is the thinnest part of the face, has few sebaceous glands, is vulnerable to dryness,
and is a special area where damage easily accumulates due to frequent facial expressions.
When fundamental improvement is difficult with general skincare,

an approach that regenerates the skin tissue itself is suitable,
and this approach is Hongdae Rejuran i.
Rejuran i is a method of injecting PN (polynucleotide) ingredients refined from salmon DNA,
formulated specifically for the eye area, into the dermis,
and it is a treatment that fundamentally regenerates thinned eye skin tissue.
At the Hongdae branch, we operate Rejuran i 1cc 1-session and 3-session options
together with cryo and sheet mask care,
so you can proceed according to your regular care plan.
In addition to Rejuran i, we also operate various Rejuran series treatments at the Hongdae branch.
For elasticity and wrinkle care,
Rejuran Healer,
a premium option for pain reduction and hydration,
Rejuran HB,for moist lip care,
Lipjuran,for neck wrinkle care,
Neck Wrinkle Rejuran,for depressed scar regeneration,
up to Rejuran S,you can choose the suitable Rejuran treatment according to the management area and purpose.
We will check the direction suitable for your eye condition and management goals directly during the consultation.If you want fundamental regeneration of thin and sensitive eye skin,
please feel free to visit Cleor Clinic Hongdae Branch.
Even before deciding on the treatment, through a preliminary consultation,
you can examine your eye condition and a suitable session plan together.
※ This content is for general information purposes, and results may vary by individual.
Please decide on accurate diagnosis and treatment through consultation with a specialist.
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