Hello.
I am Dr. Kim Dong-young, Director of Cleor Clinic Hongdae Branch.
Have you ever felt self-conscious about deep, indented scars left behind after acne has cleared,
to the point where even makeup cannot hide them?
"The spots where I had acne a long time ago are now uneven and indented.
The surface pigmentation has faded, but the indentations remain, causing my makeup to settle into them."
Indented scars are a different matter from simple hyperpigmentation.
When acne inflammation reaches deep into the dermis, the collagen and dermal structure collapse,
creating an environment where the skin heals in an indented state.
Surface care and general pigmentation treatments have limitations,
as they struggle to reach the collapsed internal structure.
While Rejuran is known primarily as a skin booster focused on hydration and elasticity,
there is a specific line within the Rejuran series dedicated to indented scars.
Hongdae Rejuran S is designed to increase PN concentration and viscosity to provide physical support to the indented area
while simultaneously promoting the production of your own collagen.
Today, I will explain how Hongdae Rejuran S differs from standard Rejuran,
and the mechanism it uses to approach scar regeneration.
What is Hongdae Rejuran S?
👉 Hongdae Rejuran S is a line from the Korean PharmaResearch Rejuran series specifically designed for indented scars, with increased PN concentration and viscosity.
It is a scar regeneration treatment that acts as a physical scaffold for the scar area while promoting self-collagen production.
Rejuran is generally known as a skin booster category focused on hydration, elasticity, and fine line smoothing.
However, PN (polynucleotide), the core ingredient of Rejuran,
is extracted from salmon and trout DNA,
and has long been used in the treatment of burns, chronic inflammation, and scars due to its role in recovering damaged skin tissue, anti-inflammation, and stimulating cell proliferation.
Rejuran S is a line within this series specialized for scar regeneration,
so it has a different PN concentration and viscosity structure than the standard Rejuran Healer.
At our Hongdae branch, it is an option used for treating indented acne scars, chickenpox scars, and traumatic scars.
Differences between Hongdae Rejuran S and standard Rejuran
👉 Hongdae Rejuran S is a specialized line with higher PN concentration and viscosity than standard Rejuran Healer, allowing it to act directly on scar tissue.
Increased PN concentration
Rejuran S has a higher PN concentration than the existing Rejuran Healer.
Higher concentrations allow for more intensive stimulation of damaged tissue recovery and cell proliferation,
making it an effective configuration for narrow and deep areas like scars.
Increased viscosity
Rejuran S is a high-viscosity (sticky) line.
The high viscosity acts as a scaffold that physically supports the collapsed skin layer under the indented scar,
creating space for the sunken skin to fill back in.
Specialized for specific areas
While standard Rejuran Healer is focused on improving overall facial skin condition,
Rejuran S is a line that acts locally on indented scar areas.
Although they are in the same PN series, they are classified into different categories based on their purpose and application area.
Mechanism of Hongdae Rejuran S
👉 Hongdae Rejuran S approaches scar regeneration through four mechanisms: acting as a physical scaffold, stimulating PN-based damaged tissue recovery, anti-inflammatory effects, and stimulating self-collagen production.
① Physical scaffold role
When the high-viscosity Rejuran S ingredient settles under an indented scar,
it physically supports the collapsed dermal structure, creating a temporary volumizing effect in the sunken area.
This supportive environment provides the time and space for collagen to regenerate.
② PN-based damaged tissue recovery stimulation
PN is an ingredient that stimulates the recovery of damaged dermal tissue.
When PN settles in areas where collagen and dermal structures have collapsed, such as scars,
it is known to activate tissue recovery signals.
③ Anti-inflammatory effect
PN is reported to assist with anti-inflammatory effects in the dermis.
It helps clear the micro-inflammatory environment remaining around the scar,
creating an environment conducive to regeneration.
④ Stimulation of self-collagen production
PN induces dermal fibroblast activity, stimulating the production of your own collagen and elastin.
As time passes, the newly generated collagen settles in the scar area,
leading to a gradual filling of the indented area.
Clinical data for standard Rejuran treatments have reported an average 37% increase in collagen density at 6 weeks post-treatment,
and up to a 68% increase at 12 weeks.
Effects and advantages of Hongdae Rejuran S
👉 The core advantages of Hongdae Rejuran S are its direct action on scar areas, simultaneous approach to immediate support and gradual regeneration,
and the fact that it is a line with fewer burdens compared to general treatments.
First, it acts directly on the scar area.
Unlike surface pigmentation care, the PN and viscous ingredients settle into the dermal structure of the indented scar,
approaching the internal environment of the scar itself.
Next, it provides both immediate support and gradual regeneration.
Immediately after treatment, the viscous ingredients provide a physical lifting effect on the indented area,
and over time, the PN-stimulated self-collagen production accumulates,
leading to gradual scar regeneration.
Finally, it is a line with fewer burdens compared to general treatments.
Unlike laser scar treatments that cause epidermal damage, this is an injection-based procedure,
so it is known to have a relatively lower downtime burden.
Hongdae Rejuran S lineup
👉 At our Hongdae branch, we offer Rejuran S for scar regeneration in 1-session and 3-session options.
Scar regeneration is not an area where significant changes occur after a single treatment,
but rather a category where changes accumulate gradually through PN action and self-collagen production.
We will discuss the session configuration that suits your scar severity and schedule during your pre-treatment consultation.
Who is Hongdae Rejuran S for?
Those with deep, indented marks left from acne
Those with past marks from chickenpox or trauma remaining on the surface
Those who feel that surface pigmentation care is insufficient
Those who find the downtime of laser scar treatments burdensome
Those looking for gradual scar regeneration through cumulative care
Side effects and precautions for Hongdae Rejuran S
👉 Hongdae Rejuran S is not a treatment where scars disappear completely after one session,
but a procedure where self-collagen production takes hold through cumulative sessions.
Mild swelling, bruising, stinging, or fine nodules may occur at the treatment site immediately after the procedure.
These are reported to subside naturally within a few days to 1-2 weeks.
In some cases after Rejuran treatment, temporary skin texture unevenness has been reported.
As the PN ingredient may be absorbed at different rates depending on the area,
fine bumps may occur for 2-4 weeks after treatment,
but most stabilize naturally over time.
Depending on the depth and shape of the scar, there are areas where standalone treatment may be limited,
so for deep and narrow ice-pick scars, it may be combined with other scar treatments in stages.
Please inform us in advance if any of the following apply to you:
If you are pregnant or breastfeeding
If you have active herpes, infection, or active acne at the treatment site
If you have a history of allergies to fish proteins such as salmon or trout
If you have autoimmune diseases, keloid tendencies, or a tendency for hypertrophic scarring
If you are regularly taking medications that increase bleeding tendencies
⚠️ Precautions before and after Hongdae Rejuran S treatment
👉 For Hongdae Rejuran S, management at each stage before and after the procedure affects recovery and the perceived results.
❓ Frequently Asked Questions (FAQ)
Q. How is Hongdae Rejuran S different from standard Rejuran Healer?
Although they are in the same Rejuran series, they are different lines with different PN concentrations and viscosities.
Rejuran Healer is focused on overall facial skin condition recovery,
while Rejuran S is specialized to act directly on indented scar areas by increasing PN concentration and viscosity.
Q. Does Hongdae Rejuran S improve all scars?
The mechanism varies depending on the shape and depth of the scar.
It is reported to be effective for relatively wide and shallow indented scars,
but for deep and narrow ice-pick scars, it may be recommended to combine it with other treatments in stages.
Q. When can I see the effects of Hongdae Rejuran S?
Immediately after treatment, the temporary support effect of the viscous ingredients is reported,
and the full scar regeneration changes occur gradually over 4-12 weeks as self-collagen production accumulates.
This varies by individual.
Q. How many sessions of Hongdae Rejuran S should I receive?
Although it depends on the severity of the scar, changes generally stabilize after 3 cumulative sessions.
For deep scars, additional sessions or combination with other treatments may be recommended,
and the number of sessions suitable for your scar condition will be determined during the pre-treatment consultation.
Q. How painful is Hongdae Rejuran S?
Numbing cream is generally applied before the procedure, and you may feel a stinging sensation during the injection.
As it is a higher-viscosity line than standard Rejuran Healer, you may feel slightly more sensation during injection,
but it is reported to be at a tolerable level for most.
Q. Can I resume daily activities immediately after receiving Hongdae Rejuran S?
As it is a treatment with relatively low downtime, you can generally resume daily activities immediately after the procedure.
Mild swelling and bruising may persist for a few days,
so it is recommended to consider your schedule before important events.
Q. Can Hongdae Rejuran S be received along with laser scar treatments?
It is an area that is often combined in stages with scar-specific lasers such as Pico Fraxel or CO2 Fraxel.
The combination schedule will be discussed during the pre-treatment consultation.
Indented scars are not just simple hyperpigmentation, but multi-layered changes where dermal collagen and internal structures have collapsed.
Surface care and general pigmentation treatments have limitations in reaching the collapsed internal structure,
which is why a line that acts directly on the dermal environment with PN has been established.
Hongdae Rejuran S is a line from the Korean PharmaResearch Rejuran series specialized for scar regeneration by increasing PN concentration and viscosity,
and it is a treatment that provides both a physical scaffold and self-collagen production in indented areas.
At our Hongdae branch, we operate various other Rejuran lines in addition to Rejuran S.
Rejuran Healer for overall facial elasticity and fine line smoothing,
Rejuran HB for reduced pain and a dewy skin condition,
Rejuran I with adjusted viscosity for the thin skin around the eyes,
Lip-specific Rejuran, and Neck-specific Rejuran for neck wrinkles,
we offer various options tailored to the area and skin type.
The line configuration suitable for your scar condition
will be confirmed during your consultation.
If you are concerned about acne marks and deep indented scars,
please feel free to visit Cleor Clinic Hongdae Branch.
Even before deciding on a treatment, we will provide detailed guidance on your skin condition and
the appropriate care direction through a pre-treatment consultation.
※ This content is for general information purposes only, and results may vary by individual.
Please decide on accurate diagnosis and treatment through consultation with a specialist.
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