Hello.
I am Director Dong-young Kim of Cleor Clinic Hongdae Branch.
When looking into skin boosters,
it can be overwhelming because there are so many names.
Rejuran, Juvelook, Lituo, Adite, Healowave...
They all say they're good, but what exactly is the difference,
and many people are unsure which one to choose.
In particular, two that are frequently mentioned lately
are Adite and Lituo.
Some say the two products are in the same category,
while others say they are different.
Today, focusing on the Adite skin booster in Hongdae,
I will explain how it is similar to and different from Lituo
as objectively as possible.
First, you need to understand what ECM is.
Beneath the visible outer layer of the skin, the epidermis,
there is a thick structure called the dermis.
Inside the dermis, there are cells,
and there is a structure that supports and connects
these cells, which is called
ECM, or Extracellular Matrix.
Within the ECM, key components such as collagen, elastin, and hyaluronic acid
that maintain skin elasticity and hydration
are intertwined like a mesh.
To use a house analogy, the ECM represents the pillars and walls.
No matter how beautiful the interior design is,
if the building structure itself weakens,
there is a limit to how much decorating the exterior can do.
As we age or as UV rays and stress accumulate,
this ECM structure begins to collapse.
The reason why collagen decreases, elasticity drops,
skin texture becomes rough, and wrinkles form
is precisely due to the weakening of the ECM.
What is the difference between conventional skin boosters and the ECM category?
Conventional skin boosters generally take two approaches.
👉PN-based products like Rejuran
send skin regeneration signals to indirectly induce
collagen production.
👉PDLLA-based products like Juvelook
stimulate collagen production using a foreign body response.
Both methods are indirect approaches that create an environment
for the skin to produce collagen on its own.
On the other hand, Adite and Lituo take a different direction.
They directly supplement the dermis
with the actual components that make up the ECM.
Using a factory analogy,
if conventional skin boosters increase the factory's operation rate,
the ECM category directly supplies the raw materials.
What kind of product is Adite?
The Adite skin booster in Hongdae is
an hADM-based ECM skin booster developed by Medpark,
a company specializing in regenerative medicine.
hADM is a material where cells and fat components are removed
from human dermal tissue,
leaving only the pure ECM structure.
It is produced under a medical-grade management system
after precisely removing cell nuclei and residual DNA,
which are the causes of immune rejection.
The core of Adite is MPT technology.
This technology is characterized by processing hADM into fine particles
of 45μm or less.
The more uniform and smaller the particles, the more evenly they disperse in the dermis,
reducing resistance and burden during injection.
It uses only AATB (American Association of Tissue Banks) certified raw materials
to meet quality and safety standards.
How is it similar to and different from Lituo?
First, let's look at the similarities between the two products.
Both Adite and Lituo are methods of directly supplementing ECM components
based on human-derived acellular dermal matrix (hADM).
They share the same principle of supplying all components
that make up the skin structure, such as collagen and elastin,rather than a single ingredient.
Both products use AATB-certified raw materials.
The differences are as follows.
Lituo is a product developed by L&C Bio,
which approaches dermal structure restoration
by micronizing hADM into a powder form.
It was the first to be launched in the domestic market,
so it has accumulated a wealth of clinical cases.
👉The structural difference is that Adite is processed into even finer particles
of 45μm or less using Medpark's MPT technology.
It is designed with more uniform and smaller particles
to ensure even distribution throughout the skin layers.
Since both products are hADM-based,
the basic approach of "supplementing skin with skin" is the same.
We will guide you on which product is more suitable for your current skin condition after a direct consultation.
What kind of changes can be expected?
Results may vary by individual.
As ECM components settle in the dermis,
they act gradually to improve
the collagen and elastin environment.
Rather than immediate volume changes,
it is a method where skin density and elasticity gradually change.
Some people experience improvements such as
finer skin texture and reduced fine lines and pores.
Since the effects are cumulative, repeating the procedure 2–3 times
often leads to more significant changes than a single session.
However, as it is a relatively new product,
it has less long-term clinical data compared to Lituo.
It is an option for those who:
Have not experienced satisfactory results with conventional skin boosters.
Feel that their skin density and elasticity have fundamentally decreased.
Want improvement of the skin structure itself rather than simple hydration.
It serves as an option for these individuals.
If you are pregnant or breastfeeding,
have a history of allergies to human tissue-derived components,
or have active inflammation on the skin, a consultation is required before the procedure.
⚠️ Precautions
On the day of the procedure, avoid rubbing or massaging the treated area forcefully.
Please refrain from alcohol, saunas, steam rooms, and strenuous exercise for one week after the procedure.
Temporary swelling, redness, or itching may occur,
most of which subside naturally within a few days.
Please maintain adequate moisturizing and apply sunscreen regularly,
and visit the clinic immediately if any adverse reactions persist.
❓ Frequently Asked Questions
Q. Which is better, the Adite skin booster in Hongdae or Lituo?
Both products are hADM-based ECM skin boosters,
and their underlying principles are the same.
The difference lies in the manufacturer and the particle processing method.
Adite is designed with finer particles of 45μm or less,
while Lituo has a longer history of clinical cases.
We will guide you on which product is more suitable for your current skin condition after a direct consultation.
Q. How is it different from conventional Rejuran or Juvelook?
Rejuran uses salmon DNA (PN) components
to indirectly induce collagen production,
while Juvelook utilizes a foreign body response with PDLLA components.
Adite and Lituo have a different mechanism altogether,
as they directly supplement the ECM components themselves.
Q. Is it effective after just one session?
Since it works by ECM components settling in the dermis
and improving the collagen environment, 2–3 cumulative sessions
often lead to more significant changes.
We recommend checking the results after one session before deciding on additional treatments.
Q. I'm worried about rejection since it's a human-derived component.
hADM is a material from which cell nuclei and residual DNA,
which cause immune rejection, have been precisely removed.
The core technology of ECM-category skin boosters is enhancing biocompatibility
through a decellularization process.
However, due to its nature as a human tissue-derived product,
those with a history of allergies require a prior consultation.
Q. Can I receive both Adite and Lituo together?
Generally, components of the same category are not injected simultaneously.
It is important to first determine which product is more suitable for your current condition.
It is natural to be confused because there are so many types of skin boosters.
The Adite skin booster in Hongdae is a next-generation skin booster
that directly addresses the collapsed skin ECM environment based on human-derived hADM.
While it is in the same category as Lituo, Adite is characterized by
an even more finely processed particle structure using MPT technology.
At Cleor Clinic Hongdae Branch, we directly assess your current skin condition
and provide honest guidance on the best choice for your situation
among various skin boosters, including Adite and Lituo.
We will first check your current condition. Please feel free to inquire.
※ This content is for general informational purposes, and results may vary by individual.
Please make decisions regarding accurate diagnosis and procedures through a consultation with a specialist.